Our work is supported by both federal and private funding, and both are critical for fostering a highly innovative and sustainable research program aimed at advancing our understanding of the molecular mechanisms that regulate gene expression in cancer and aging, as well as developing novel therapeutic approaches for cancer and rare diseases.
How to support our research
If you are interested in supporting our work, you can contact the JAX Advancement Office https://www.jax.org/give/contact (indicate Dr. Olga Anczukow in comments) or contact Dr. Olga Anczukow directly.
Current grant support:
NIH/NCI, R01 CA277495, 05/01/2024–04/30/2029
PI: Lewis, R AK (Co-investigator Anczuków, O.)
Regulation of RBP function during EMT
NIH/AI, U19 AI142733-06, 03/21/2024–02/28/2029
PI: Palucka AK (Co-investigator Anczuków, O.)
Modulation of Lung Immune Responses to Viral Infection
NIH/NIAMS, P50 AR070594, 09/01/2022–05/31/2027
PI: Pascual, V. (Co-investigator Anczuków, O.)
Center for Lupus Research – Center for Lupus Research – Project 2
NIH/NCI, R01 CA248317, 02/09/2021–01/31/2026
PI: Anczuków-Camarda, O.
MYC-regulated RNA Binding Protein Networks and Spliced Isoforms Driving Cancer
NIH/NIGMS, R01 GM138541,07/01/2020–04/30/2025
PI: Anczuków-Camarda, O.
Mechanisms of post-transcriptional regulation of splicing factors
NIH/NIA, R21 AG080243, 09/01/2023–05/31/2024
PI: Anczukow-Camarda, O. Chuang, J. (Multi-PI)
Building a spatial transcriptomics infrastructure for isoform profiling in aging pre-neoplastic tissues
Hevolution Foundation, R21/R33 AGE-002, 01/15/2023– 01/14/2028
PI: Anczukow-Camarda, O. Chuang, J. (Multi-PI)
Building a spatial transcriptomics infrastructure for isoform profiling in aging epithelial tissues
NIH/NCI, P30 CA034196S1, 04/01/2021–11/30/2024
PI: Palucka, K. (Co-investigator Anczuków, O.)
Cancer Center Support Grant
The Jackson Laboratory Cancer Center Award, P30 CA034196. 04/15/2024–12/31/2024
PI: Anczuków, O.
Mapping transcriptomic changes associated with STAT2 isoforms in lung cancer cell lines
Completed grant support:
The Jackson Laboratory Cancer Center Award, P30 CA034196, 09/01/2023–02/28/2024
PI: Anczuków, O.
Enhancing long-read single cell sequencing methods
The Scott R. MacKenzie Foundation, 01/01/2023–12/31/2023
PI: Anczuków, O.
Identifying novel drivers of age-related breast cancers
The Jackson Laboratory Director’s Innovation Award, 01/01/2022–12/31/2023
PI: Anczuków, O. and Hinson, JT. (Multi-PI)
Sex-dependent (epi)transcriptomic responses to the aging HFpEF heart
The Jackson Laboratory Cancer Center Award, P30 CA034196, 12/01/2022–11/30/2023
PI: Anczuków, O.
Defining splicing alterations driven by hormones and metabolic stress in aged mammary tissues
NIH/NCI, R01 CA230031, 06/05/2018–05/31/2023
PI: Chuang, J. (Co-investigator Anczuków, O.)
Quantitative Computational Methods to Accurately Measure Tumor Heterogeneity in Solid Tumors to Inform Development of Evolution-based Treatment Strategies
The Jackson Laboratory Cancer Center Award, P30 CA034196. 04/12/2022–03/31/2023
PI: Liu E., Anczuków, O. (Multi-PI)
RNA spliced isoforms in acquired resistance to chemotherapy for triple negative breast cancer
The Jackson Laboratory Cancer Center Award, P30 CA034196, 05/01/2021–12/31/2022
PI: Anczuków, O.
The poison exon of oncogenic splicing factor TRA2Β acts as a tumor suppressor lncRNA across multiple tumor types
Linda Tallen and David Paul Kane Education and Research Foundation, 02/01/2022–10/31/2022
PI: Anczuków, O.
Identifying novel drivers of age-related breast cancers
The Jackson Laboratory Cancer Award, P30 CA034196, 11/01/2020–11/30/2021
PI: Anczuków, O. and Ucar, D. (Multi-PI)
Age-related changes in transcriptional regulatory programs of mammary gland cells as a risk factor for breast cancer
NIH/AI, U19 AI142733-03, 07/01/2021–10/09/2021
PI: Palucka, A. (Co-investigator Anczuków, O.)
Modulation of Lung Immune Responses to Viral Infection
Sanofi US Services, SANOFI-SRA-FY19-JFB, 01/02/2019-07/30/2021
PI: Banchereau, J. (Co-investigator Anczuków, O.)
Identification of Novel Therapeutic Targets in Triple Negative Breast Cancer and Ovarian Carcinoma through Long-Read Isoform Profiling
The Jackson Laboratory Cancer Center Award, P30 CA034196, 11/16/2020–12/31/2020
PI: Anczuków, O. and Ucar, D. (Multi-PI)
Splicing alterations during aging and breast cancer
V Foundation, 10/01/2018–09/30/2020
PI: Anczuków, O.
Uncovering Genomic Alterations in the Breast, Paving the Road to Early Cancer Detection and Prevention
The Jackson Laboratory Cancer Center Award, P30 CA034196, 03/01/2018–06/30/2019
PI: Anczuków, O.
Developing models and tools to dissect the role of splicing factor TRA2β in epithelial tumors
JAX-Purdue Pilot Award, 01/01/2018–08/31/2019
PI: Anczuków, O. and Solorio, L. (Multi-PI)
The role of extracellular matrix driven splice variants in drug resistance and metastasis
NIH/NCI, R00 CA178206, 07/01/2016–06/30/2019
PI: Anczuków-Camarda, O.
Role of Splicing Factors in Breast Cancer
Completed Research Support prior to 2016
NIH/NCI, K99 CA178206, 09/01/2013–06/30/2016
PI: Anczuków-Camarda, O.
Role of Splicing Factors in Breast Cancer
Terri Brodeur Breast Cancer Foundation, 01/01/2013–12/31/2014
PI: Anczuków-Camarda, O.
Measuring Transcriptome-wide Changes in Alternative Splicing in Cancer
Susan G. Komen for the Cure Foundation, 06/04/2009–06/03/2012
PI: Anczukow-Camarda, O. and Krainer A.R.
Role of Alternative Splicing in Epithelial Cell Transformation
French Foundation for Medical Research, 01/01/2008–12/31/2008
PI: Anczukow-Camarda, O.
Role of Alternative Splicing Factors in Initiation and Progression of Human Breast Cancer
Cancer Research Foundation ‘Ligue Contre le Cancer’, 09/01/2006-31/12/2006
PI: Anczuków, O.
Molecular consequences of mutations in breast cancer predisposing genes
Cancer Research Foundation ‘Ligue Contre le Cancer de Saône-et-Loire’, 09/01/2004 08/31/2006
PI: Anczuków, O.
Molecular consequences of mutations in breast cancer predisposing genes